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Beilstein J. Org. Chem. 2014, 10, 2367–2376, doi:10.3762/bjoc.10.247
Graphical Abstract
Figure 1: Structures of the repeating unit of MenX CPS and synthetic oligomers 1–3.
Scheme 1: Reagents and conditions: a) NiCl2/NaBH4, MeOH; b) Ac2O, 86% over 2 steps; c) TBAF, THF, −40 °C to r...
Scheme 2: Reagents and conditions: a) PivCl in pyridine, then I2 in 19:1 pyridine/H2O, then 1 M TEAB (45%); b...
Scheme 3: Reagents and conditions: a) SIDEA, Et3N, DMSO: 11 (64%), 12 (49%), 13 (51%); b) CRM197, 100 mM NaPi...
Figure 2: IgG levels detected at OD = 1 in individual post 3 sera (sera collected two weeks after the third i...
Figure 3: A) IgG levels detected at OD = 1 in individual post 3 sera of BALB/c mice immunization at 0.3 μg sa...